| Product Name | Anti-SEC31A antibody-RBITC |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | RBITC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | SEC31A |
|---|---|
| Gene Synonyms | 1110003H02Rik 1810024J13Rik ABP125 ABP130 CLSD D3S1231E HPBKS hSec23A HSPC275 HSPC334 Msec23 NEDSOSB npp-20 SEC13L1 SEC13R Sec23r SEC31L1 VAP1 |
| Gene Full Name | SEC31 homolog A, COPII component |
| Gene Summary | The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] |
| Alternative Names | cop ii GATOR complex protein SEC13 GATOR2 complex protein SEC13 SEC13 homolog nuclear pore and COPII coat complex component SEC13 homolog nuclear pore and COPII coating complex component SEC13 related SEC13-like 1 SEC13-like protein 1 SEC13-related protein Sec23 homolog A coat complex II component SEC23 homolog A COPII coat complex component SEC23-related protein A SEC24 family member A SEC24 homolog A COPII coat complex component SEC24 related gene family member A SEC24-related protein A Sec31 homolog A SEC31 homolog A COPII coat complex component SEC31 homolog A COPII coating complex component SEC31-like 1 SEC31-like protein 1 SEC31-related protein A transport protein vesicle associated protein vesicle-associated protein 1 web1-like protein yeast Sec31p homolog |
| Molecular Weight(MW) | 133kDa |
| Cellular Localization | Cytoplasm, Cytoplasmic vesicle |
| SwissProt ID | O94979 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
