| Gene Symbol |
CHRNE
|
| Gene Synonyms |
ACHRE AChrepsilon Acre CMS1A1 CMS1D CMS1E CMS2A CMS4A CMS4B CMS4C FCCMS FIM1 FIMG FIMG1 MGI nAChR nAChRE SCCMS |
| Gene Full Name |
cholinergic receptor nicotinic epsilon subunit |
| Gene Summary |
Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome. [provided by RefSeq, Sep 2009] |
| Alternative Names |
acetylcholine receptor acetylcholine receptor epsilon acetylcholine receptor nicotinic epsilon (muscle) AchR epsilon subunit ACHRG cholinergic receptor cholinergic receptor nicotinic epsilon cholinergic receptor nicotinic epsilon (muscle) cholinergic receptor nicotinic epsilon polypeptide epsilon-subunit gene for acetylcholine receptor epsilon subunit MGC133376 myasthenia gravis familial infantile 1 nicotinic acetylcholine receptor epsilon subunit |
| Molecular Weight(MW) |
55kDa(observed:60kDa) |
| Cellular Localization |
Cell membrane,Cell junction, synapse, postsynaptic cell membrane |