| Product Name | Anti-LILRB2 antibody-RBITC |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | RBITC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Antigen peptide affinity chromatography |
| Gene Symbol | LILRB2 |
|---|---|
| Gene Synonyms | CD85D ILT-4 ILT4 LIR-2 LIR2 MIR-10 MIR10 |
| Gene Full Name | leukocyte immunoglobulin like receptor B2 |
| Gene Summary | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names | CD85 antigen-like family member D CD85d antigen Ig-like transcript 4 immunoglobulin superfamily leucocyte Ig-like receptor B2 leukocyte immunoglobulin-like receptor subfamily B (with TM and ITIM domains) member 2 LIR2CD85D MIR10LILRA6 monocyte/macrophage Ig-related receptor monocyte/macrophage immunoglobulin-like receptor 10 myeloid inhibitory receptor 10 |
| Molecular Weight(MW) | 65kDa |
| Cellular Localization | Membrane |
| SwissProt ID | Q8N423 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
