ICC/IF
Immunofluorescence analysis of U251 cells using ARFGAP1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-ARFGAP1 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ARFGAP1 |
|---|---|
| Gene Synonyms | Arf GAP1 ARF1GAP HRIHFB2281 |
| Gene Full Name | ARF GTPase activating protein 1 |
| Gene Summary | The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| Alternative Names | ADP ribosylation factor GTPase activating protein 1 ADP-ribosylation factor 1 GTPase activating protein ADP-ribosylation factor 1 GTPase-activating protein ADP-ribosylation factor GTPase activating protein 1 ARF GAP 1 ARF1 GAP ARF1-directed GTPase-activating protein ArfGAP1 GAP protein HRIHFB2281 RP11-261N11.1 |
| Molecular Weight(MW) | 45kDa |
| Cellular Localization | Cytoplasm,Golgi apparatus,Associates with the Golgi complex |
| SwissProt ID | Q8N6T3 |
|---|
ICC/IF
Immunofluorescence analysis of U251 cells using ARFGAP1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
