| Gene Symbol |
GRIK3
|
| Gene Synonyms |
9630027E11 EAA5 GLR7 GluK3 Glur-7 GLUR7 GluR7-3 GluR7a |
| Gene Full Name |
glutamate ionotropic receptor kainate type subunit 3 |
| Gene Summary |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq, Jul 2008] |
| Alternative Names |
dJ1090M5.1 (glutamate receptor ionotropic kainate 3 (GLUR7)) excitatory amino acid receptor 5 gluR-7 glutamate receptor glutamate receptor 7 glutamate receptor subunit glutamate receptor subunit kainate subtype glutamate receptor ionotropic kainate 3 ionotropic glutamate receptor subunit |
| Molecular Weight(MW) |
104kDa |
| Cellular Localization |
Cell membrane,Cell junction |