WB
Western blot analysis using CD195 antibody against Mouse brain tissue(1) .| Product Name | Anti-CD195 antibody-poly-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | poly-HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CCR5 |
|---|---|
| Gene Synonyms | AM4-7 CC-CKR-5 CCCKR5 CCR-5 CD195 CKR-5 CKR5 CMKBR5 IDDM22 |
| Gene Full Name | C-C motif chemokine receptor 5 |
| Gene Summary | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles; the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2015] |
| Alternative Names | C-C CKR-5 C-C motif chemokine receptor 5 A159A CC-CKR-5 CD195 antigen chemokine (C-C motif) receptor 5 chemokine (C-C) receptor 5 chemokine receptor CCR5 chemokine recptor CCR5 Delta32 chemr13 HIV-1 fusion coreceptor MIP-1 alpha receptor mutant C-C motif chemokine receptor |
| Molecular Weight(MW) | 41kDa |
| Cellular Localization | Cell membrane |
| SwissProt ID | P51681 |
|---|
WB
Western blot analysis using CD195 antibody against Mouse brain tissue(1) .| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
