ICC/IF
Immunofluorescence analysis of C2C12 cells using CHRND antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-CHRND antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CHRND |
|---|---|
| Gene Synonyms | ACHRD CMS2A CMS3A CMS3B CMS3C FCCMS SCCMS |
| Gene Full Name | cholinergic receptor nicotinic delta subunit |
| Gene Summary | The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015] |
| Alternative Names | acetylcholine receptor acetylcholine receptor nicotinic delta (muscle) cholinergic receptor cholinergic receptor nicotinic delta cholinergic receptor nicotinic delta (muscle) cholinergic receptor nicotinic delta polypeptide |
| Molecular Weight(MW) | 59kDa |
| Cellular Localization | Cell junction, Cell membrane |
| SwissProt ID | Q07001 |
|---|
ICC/IF
Immunofluorescence analysis of C2C12 cells using CHRND antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
