ICC/IF
Immunofluorescence analysis of MCF-7 cells using CD191 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-CD191 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CCR1 |
|---|---|
| Gene Synonyms | CD191 CKR-1 CKR1 CMKBR1 HM145 Mip-1a-R MIP1aR SCYAR1 |
| Gene Full Name | C-C motif chemokine receptor 1 |
| Gene Summary | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008] |
| Alternative Names | C-C CKR-1 CC-CKR-1 CCR-1 chemokine (C-C motif) receptor 1 chemokine (C-C) receptor 1 chemokine receptor LD78 receptor macrophage inflammatory protein 1-alpha receptor MIP-1 alpha R MIP-1 alphaR MIP-1alpha-R RANTES receptor RANTES-R |
| Molecular Weight(MW) | 41kDa(observed：35kDa) |
| Cellular Localization | Cell membrane |
| SwissProt ID | P32246 |
|---|
ICC/IF
Immunofluorescence analysis of MCF-7 cells using CD191 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
