| Product Name | Anti-CD105 antibody-RBITC |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | RBITC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ENG |
|---|---|
| Gene Synonyms | CD105 END Endo HHT1 ORW1 S-endoglin |
| Gene Full Name | endoglin |
| Gene Summary | This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013] |
| Alternative Names | CD105 antigen cell surface MJ7/18 antigen circulating isoform of endoglin TGF-beta receptor type III co-receptor endoglin precursor ORW soluble endoglin TGF-beta receptor III homolog transmembrane glycoprotein |
| Molecular Weight(MW) | 71kDa |
| Cellular Localization | Membrane |
| SwissProt ID | P17813 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
