ICC/IF
Immunofluorescence analysis of MCF-7 cells using MTHFR antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-MTHFR antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MTHFR |
|---|---|
| Gene Synonyms | MTHFR Methylenetetrahydrofolate reductase |
| Gene Full Name | methylenetetrahydrofolate reductase |
| Gene Summary | The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009] |
| Alternative Names | 5 10-methylenetetrahydrofolate reductase 5 10-methylenetetrahydrofolate reductase (NADPH) methylenetetrahydrofolate reductase (NAD(P)H) MTHFR MTHFR long isoform MTHFR short isoform RP11-56N19.4 |
| Molecular Weight(MW) | 75kDa |
| Cellular Localization | Cytosol |
| SwissProt ID | P42898 |
|---|
ICC/IF
Immunofluorescence analysis of MCF-7 cells using MTHFR antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
