This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011]
Alternative Names
C-type lectin protein CLL-1 C-type lectin superfamily C-type lectin-like molecule 1 C-type lectin-like molecule-1 DCAL-2 dendritic cell-associated lectin 2 killer cell C-type lectin-like receptor L1 MICL-alpha type II transmembrane protein MICL-beta type II transmembrane protein MICL-gamma type II transmembrane protein myeloid inhibitory C-type lectin-like receptor