WB
Western blot analysis using HIFIA antibody against Mouse brain tissue(1).IHC
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissues using HIF1A antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using HIF1A antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using HIF1A antibody with DAB staining.| Product Name | Anti-HIFIA antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | HIF1A |
|---|---|
| Gene Synonyms | bHLHe78 HIF-1-alpha HIF-1A HIF-1alpha HIF1 HIF1-ALPHA HIF1a HIF1alpha MOP1 PASD8 XELAEV_18039792mg XELAEV_18041137mg xhif1a |
| Gene Full Name | hypoxia inducible factor 1 subunit alpha |
| Gene Summary | This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011] |
| Alternative Names | ARNT interacting protein ARNT-interacting protein ARNT2 basic-helix-loop-helix-PAS protein MOP1 class E basic helix-loop-helix protein 78 HIF hif 1 hif 1a HIF-1 alpha HIF-1-alpha HIF-1alpha 786 HIF1 alpha HIF1-alpha hypoxia inducible factor 1 alpha subunit hypoxia inducible factor 1 alpha subunit L homeolog hypoxia inducible factor 1 alpha subunit (basic helix-loop-helix transcription factor) Hypoxia-inducible factor 1 alpha hypoxia-inducible factor 1 alpha subunit (basic helix-loop-helix transcription factor) hypoxia-inducible factor 1 alpha subunit (basic helix-loop-helix transcription factor) L homeolog hypoxia-inducible factor1alpha member of PAS protein 1 member of PAS superfamily 1 PAS domain-containing protein 8 transcription factor transcription factor hypoxia-inducible factor 1a transcription factor RH1F-1 |
| Molecular Weight(MW) | 92kDa(observed：100kDa) |
| Cellular Localization | Cytoplasm,Nucleus,Nucleus speckle |
| SwissProt ID | Q16665 |
|---|
WB
Western blot analysis using HIFIA antibody against Mouse brain tissue(1).
IHC
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissues using HIF1A antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using HIF1A antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using HIF1A antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
