| Product Name | Anti-TNFRSF10B antibody-RBITC |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | RBITC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | TNFRSF10B |
|---|---|
| Gene Synonyms | CD262 DR5 KILLER KILLER/DR5 Ly98 MK TRAIL-R2 TRAILR2 TRICK2 TRICK2A TRICK2B TRICKB ZTNFR9 |
| Gene Full Name | TNF receptor superfamily member 10b |
| Gene Summary | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009] |
| Alternative Names | apoptosis inducing protein TRICK2A/2B apoptosis inducing receptor TRAIL-R2 cytotoxic TRAIL receptor-2 death domain containing receptor for TRAIL/Apo-2L death receptor 5 dr-5 DR4 homolog Fas-like protein KILLER/DR5 TRAIL death-inducing receptor p53-regulated DNA damage-inducible cell death receptor(killer) sCD262 second apoptosis inducing receptor for TRAIL apoptosis-mediating receptor for TRAIL soluble CD262 TNF-related apoptosis-inducing ligand receptor 2 TNFR family member TNFRSF10B tumor necrosis factor receptor superfamily member 10b tumor necrosis factor receptor-like protein ZTNFR9 |
| Molecular Weight(MW) | 47kDa |
| Cellular Localization | Membrane |
| SwissProt ID | O14763 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
