ICC/IF
Immunofluorescence analysis of C2C12 cells using WNK3 antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.IF-P
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using WNK3 antibody with DAB staining.| Product Name | Anti-WNK3 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | WNK3 |
|---|---|
| Gene Synonyms | MRXS2 PRKWNK3 PRS RGD1563131 Wnk3-ps |
| Gene Full Name | WNK lysine deficient protein kinase 3 |
| Gene Summary | This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| Alternative Names | kinase lacks lysine 3 serine/threonine-protein kinase WNK3 Prieto X-linked mental retardation syndrome PRKWNK 3 protein kinase lysine-deficient 3 protein kinase with no lysine 3 WNK 3 WNK lysine deficient protein kinase 3 pseudogene |
| Molecular Weight(MW) | 198kDa |
| Cellular Localization | Cytoplasm |
| SwissProt ID | Q9BYP7 |
|---|
ICC/IF
Immunofluorescence analysis of C2C12 cells using WNK3 antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.
IF-P
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using WNK3 antibody with DAB staining.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
