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Anti-EVC2 antibody-AF488

Catalog Number:OM661658-AF488
Human;Mouse;Rat
OM661658-AF488
Discount Price
OM661658-AF488-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-EVC2 antibody-AF488
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation AF488
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol EVC2
Gene Synonyms LBN
WAD
Gene Full Name EvC ciliary complex subunit 2
Gene Summary This gene encodes a protein that functions in bone formation and skeletal development. Mutations in this gene, as well as in a neighboring gene that lies in a head-to-head configuration, cause Ellis-van Creveld syndrome, an autosomal recessive skeletal dysplasia that is also known as chondroectodermal dysplasia. Mutations in this gene also cause acrofacial dysostosis Weyers type, also referred to as Curry-Hall syndrome, a disease that combines limb and facial abnormalities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Alternative Names Ellis van Creveld syndrome 2
ellis-van Creveld syndrome protein 2
Molecular Weight(MW) 147kDa
Cellular Localization Cell membrane;Cytoplasm, cytoskeleton, cilium basal body;Cell projection, cilium;Cell projection, cilium membrane;Nucleus
Database Links
SwissProt ID Q86UK5
Application

ICC/IF

Immunofluorescence analysis of C2C12 cells using EVC2 antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.

IF-P

Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using EVC2 antibody with DAB staining.

IF-P

Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using EVC2 antibody with DAB staining.
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300,40% Glycerol.
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