ICC/IF
Immunofluorescence analysis of C2C12 cells using EVC2 antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.| Product Name | Anti-EVC2 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Antigen peptide affinity chromatography |
| Gene Symbol | EVC2 |
|---|---|
| Gene Synonyms | LBN WAD |
| Gene Full Name | EvC ciliary complex subunit 2 |
| Gene Summary | This gene encodes a protein that functions in bone formation and skeletal development. Mutations in this gene, as well as in a neighboring gene that lies in a head-to-head configuration, cause Ellis-van Creveld syndrome, an autosomal recessive skeletal dysplasia that is also known as chondroectodermal dysplasia. Mutations in this gene also cause acrofacial dysostosis Weyers type, also referred to as Curry-Hall syndrome, a disease that combines limb and facial abnormalities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
| Alternative Names | Ellis van Creveld syndrome 2 ellis-van Creveld syndrome protein 2 |
| Molecular Weight(MW) | 147kDa |
| Cellular Localization | Cell membrane;Cytoplasm, cytoskeleton, cilium basal body;Cell projection, cilium;Cell projection, cilium membrane;Nucleus |
| SwissProt ID | Q86UK5 |
|---|
ICC/IF
Immunofluorescence analysis of C2C12 cells using EVC2 antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
