ICC/IF
Immunofluorescence analysis of NIH3T3 cells using SASH1 antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.| Product Name | Anti-SASH1 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | SASH1 |
|---|---|
| Gene Synonyms | 1100001C18Rik 2500002E12Rik A330076K04Rik CAPOK dJ323M4.1 DUH DUH1 mKIAA0790 SH3D6A |
| Gene Full Name | SAM and SH3 domain containing 1 |
| Gene Summary | This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients. [provided by RefSeq, Oct 2016] |
| Alternative Names | proline-glutamate repeat-containing protein putative adapter and scaffold protein 1 |
| Molecular Weight(MW) | 136kDa |
| Cellular Localization | Cytoplasm |
| SwissProt ID | O94885 |
|---|
ICC/IF
Immunofluorescence analysis of NIH3T3 cells using SASH1 antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
