This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Alternative Names
MGC10556 MGC10558 MGC29959 MGC3837 MGC4423 OPA-interacting protein 1 similar to ZRP-1 and TRIP6 tcag7.1300 thyroid hormone receptor interacting protein 6 TR-interacting protein 6 TRIP-6 Trip6 ZRP-1 zyxin related protein 1 zyxin-related protein 1