ICC/IF
Immunofluorescence analysis of NIH3T3 cells using MMP17 antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.| Product Name | Anti-MMP17 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MMP17 |
|---|---|
| Gene Synonyms | MMP-17 MT4-MMP MT4MMP MTMMP4 |
| Gene Full Name | matrix metallopeptidase 17 |
| Gene Summary | This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor. Elevated expression of the encoded protein has been observed in osteoarthritis and multiple human cancers. [provided by RefSeq, Jan 2016] |
| Alternative Names | matrix metallo protease matrix metallopeptidase 17 (membrane-inserted) matrix metalloproteinase 17 matrix metalloproteinase 17 (membrane-inserted) membrane-type matrix metalloproteinase 4 membrane-type-4 matrix metalloproteinase MMP MMPs MT-MMP 4 |
| Molecular Weight(MW) | 66kDa |
| Cellular Localization | Cell membrane;Secreted, extracellular space, extracellular matrix |
| SwissProt ID | Q9ULZ9 |
|---|
ICC/IF
Immunofluorescence analysis of NIH3T3 cells using MMP17 antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
