ICC/IF
Immunofluorescence analysis of C2C12 cells using EDNRB antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-EDNRB antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | EDNRB |
|---|---|
| Gene Synonyms | ABCDS Ednra ET-B ET-BR ETB ETB1 ETBR ETR-b ETRB HSCR HSCR2 Sox10m1 WS4A |
| Gene Full Name | endothelin receptor type B |
| Gene Summary | The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016] |
| Alternative Names | AU022549 endothelin B receptor endothelin receptor non-selective type endothelin receptor subtype B1 ET-B Et-b receptor Et-b-r ET-BR ET-RB Etb receptor Etb-svr G-protein coupled receptor Hirschsprung disease 2 piebald RP11-318G21.1 |
| Molecular Weight(MW) | 49kDa(observed：60kDa) |
| Cellular Localization | Cell membrane |
| SwissProt ID | P24530 |
|---|
ICC/IF
Immunofluorescence analysis of C2C12 cells using EDNRB antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
