| Gene Symbol |
IFNGR2
|
| Gene Synonyms |
AF-1 IFGR2 IFNGT1 IMD28 |
| Gene Full Name |
interferon gamma receptor 2 |
| Gene Summary |
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq, Jul 2008] |
| Alternative Names |
IFN-gamma receptor 2 IFN-gamma-R-beta IFN-gamma-R2 IFNgR2 interferon gamma receptor accessory factor-1 interferon gamma receptor beta chain interferon gamma transducer 1 |
| Molecular Weight(MW) |
37kDa(observed:40kDa) |
| Cellular Localization |
Cell membrane;Golgi apparatus membrane;Endoplasmic reticulum membrane;Cytoplasm |