ICC/IF
Immunofluorescence analysis of NIH3T3 cells using S1PR5 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-S1PR5 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Antigen peptide affinity chromatography |
| Gene Symbol | S1PR5 |
|---|---|
| Gene Synonyms | Edg-8 EDG8 lpB4 S1P5 SPPR-1 SPPR-2 |
| Gene Full Name | sphingosine-1-phosphate receptor 5 |
| Gene Summary | The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008] |
| Alternative Names | endothelial differentiation G-protein-coupled receptor 8 endothelial differentiation sphingolipid G-protein-coupled receptor 8 G protein-coupled receptor lysophospholipid receptor B4 nerve growth factor-regulated G-protein-coupled receptor 1 NRG-1 S1P receptor 5 S1P receptor Edg-8 S1P(5) receptor S1P5 sphingosine 1-phosphate receptor Edg-8 sphingosine 1-phosphate receptor EDG8 sphingosine-1-phosphate receptor LPB4 |
| Molecular Weight(MW) | 41kDa |
| Cellular Localization | Cell membrane |
| SwissProt ID | Q9H228 |
|---|
ICC/IF
Immunofluorescence analysis of NIH3T3 cells using S1PR5 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
