| Gene Symbol |
SMOC2
|
| Gene Synonyms |
1700056C05Rik 5430426J21Rik bA270C4A.1 bA37D8.1 dJ421D16.1 DTDP1 DTDP1A MST117 MSTP117 MSTP140 SMAP2 Smoc2l |
| Gene Full Name |
SPARC related modular calcium binding 2 |
| Gene Summary |
This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
| Alternative Names |
secreted modular calcium-binding protein 2 SMAP-2 SMOC-2 smooth muscle associated protein 2 thyroglobulin type-1 repeat containing protein |
| Molecular Weight(MW) |
49kDa |
| Cellular Localization |
Secreted, extracellular space, extracellular matrix, basement membrane |