ICC/IF
Immunofluorescence analysis of C2C12 cells using CUBN antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.IF-P
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using CUBN antibody with DAB staining.IF-P
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using CUBN antibody with DAB staining.| Product Name | Anti-CUBN antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CUBN |
|---|---|
| Gene Synonyms | D2Wsu88e GP280 IFCR IGS IGS1 MGA1 |
| Gene Full Name | cubilin |
| Gene Summary | Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia. [provided by RefSeq, Jul 2008] |
| Alternative Names | 460 kDa receptor cubilin cubilin (intrinsic factor-cobalamin receptor) Cubulin glycoprotein 280 intestinal intrinsic factor receptor intrinsic factor-cobalamin receptor intrinsic factor-vitamin B12 endocytic receptor HDL endocytic receptor intrinsic factor-vitamin B12 receptor membrane receptor protein |
| Molecular Weight(MW) | 398kDa |
| Cellular Localization | Apical cell membrane;Cell membrane;Membrane, coated pit;Endosome;Lysosome membrane |
| SwissProt ID | O60494 |
|---|
ICC/IF
Immunofluorescence analysis of C2C12 cells using CUBN antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.
IF-P
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using CUBN antibody with DAB staining.
IF-P
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using CUBN antibody with DAB staining.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
