ICC/IF
Immunofluorescence analysis of C2C12 cells using MASP2 antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.| Product Name | Anti-MASP2 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MASP2 |
|---|---|
| Gene Synonyms | MAP-2 MAP19 MASP-2 MASP1P1 sMAP |
| Gene Full Name | MBL associated serine protease 2 |
| Gene Summary | This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] |
| Alternative Names | mannan binding lectin serine peptidase 2 mannan-binding mannan-binding lectin serine peptidase 1 pseudogene 1 mannan-binding lectin serine peptidase 2 mannan-binding lectin serine protease 1 pseudogene 1 mannose-binding lectin associated protein 19 mannose-binding lectin-associated serine protease 2 mannose-binding protein-associated serine protease 2 MBL-associated plasma protein of 19 kD small MBL-associated protein |
| Molecular Weight(MW) | 75kDa |
| Cellular Localization | Secreted;Cell surface |
| SwissProt ID | O00187 |
|---|
ICC/IF
Immunofluorescence analysis of C2C12 cells using MASP2 antibody (green). Blue: DAPI fluorescent DNA dye.Cells are fixed in 4% paraformaldehyde at room temperature for 15 minutes.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
