ICC/IF
Immunofluorescence analysis of NIH3T3 cells using GABRA1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-GABRA1 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | GABRA1 |
|---|---|
| Gene Synonyms | DEE19 ECA4 EIEE19 EJM EJM5 GABAA-alpha1 GABAAR-alpha1 Gabra-1 |
| Gene Full Name | gamma-aminobutyric acid type A receptor subunit alpha1 |
| Gene Summary | This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names | GABA(A) receptor subunit alpha-1 GABA(A) receptor alpha 1 GABAA alpha 1 GABAAR alpha1 GABAAR subunit alpha-1 GABRA 1 gamma-aminobutyric acid gamma-aminobutyric acid (GABA) A receptor alpha 1 gamma-aminobutyric acid (GABA) A receptor subunit alpha 1 gamma-aminobutyric acid (GABA-A) receptor subunit alpha 1 gamma-aminobutyric acid A receptor alpha 1 gamma-aminobutyric acid type A receptor alpha1 subunit |
| Molecular Weight(MW) | 51kDa |
| Cellular Localization | Postsynaptic cell membrane;Cell membrane;Cytoplasmic vesicle membrane |
| SwissProt ID | P14867 |
|---|
ICC/IF
Immunofluorescence analysis of NIH3T3 cells using GABRA1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
