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Anti-TRPM6T antibody-HRP

Catalog Number:OM661779-HRP
Human;Mouse;Rat
WB;IHC
OM661779-HRP
Discount Price
OM661779-HRP-100ul
100ul
Product Profile
Product Name Anti-TRPM6T antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol TRPM6
Gene Synonyms CHAK2
HMGX
HOMG
HOMG1
HSH
TRPM6/CHAK2
Gene Full Name transient receptor potential cation channel subfamily M member 6
Gene Summary This gene is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Apr 2010]
Alternative Names ChaK2
protein kinase/ion channel
channel kinase 2
ion channel of the TRPM subfamily
subfamily M
melastatin-related TRP cation channel 6
putative cation channel subfamily M member 6
transient receptor potential cation channel 6/channel-kinase 2
transient receptor potential cation channel subfamily M member 6
transient receptor potential cation channel subfamily M member 6 variant
TRPM6a
TRPM6a-t
TRPM6b
TRPM6c
Molecular Weight(MW) 231kDa
Cellular Localization Cell membrane;Apical cell membrane;Nucleus
Database Links
SwissProt ID Q9BX84
Application

WB

Western blot analysis using TRPM6 antibody against Cos-7(1) cell .

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using TRPM6 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human muscle tissues using TRPM6 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using TRPM6 antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300,40% Glycerol.
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