This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008]
Alternative Names
homeo box 2C homeo box B7 homeo box c1 protein homeobox c1 protein homeobox protein homeobox protein HHO.C1 homeobox protein Hox-2.3 homeobox protein Hox-2C homeobox protein MH-22B homeobox protein MuB1 Hox-23 TATAA binding protein