ICC/IF
Immunofluorescence analysis of HUVEC cells using LAMA3 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-LAMA3 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | LAMA3 |
|---|---|
| Gene Synonyms | BM600 E170 JEB2A JEB2B JEB2C LAMNA LOCS |
| Gene Full Name | laminin subunit alpha 3 |
| Gene Summary | The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| Alternative Names | basement membrane protein BM600 150kD subunit Epiligrin epiligrin 170 kda subunit epiligrin alpha 3 subunit kalinin 165kD subunit kalinin subunit alpha LAM3 alpha-3 subunit LAMA3A LAMA3B1 LAMA3B2 laminin 5 alpha-3 subunit laminin A3 laminin alpha 3 (nicein (150kD) kalinin (165kD) BM600 (150kD) epilegrin) Laminin-5 laminin-5 alpha 3 chain laminin-5 subunit alpha laminin-6 subunit alpha laminin-7 subunit alpha nicein 150kD subunit nicein subunit alpha |
| Molecular Weight(MW) | 366kDa |
| Source | Rabbit |
| Cellular Localization | Secreted, extracellular space, extracellular matrix, basement membrane |
| SwissProt ID | Q16787 |
|---|
ICC/IF
Immunofluorescence analysis of HUVEC cells using LAMA3 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
