| Gene Symbol |
HTR2A
|
| Gene Synonyms |
5-HT-2 5-HT-2A 5-HT2A 5Ht-2 E030013E04 Htr-2 HTR2 |
| Gene Full Name |
5-hydroxytryptamine receptor 2A |
| Gene Summary |
This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
| Alternative Names |
5-HT-2 5-HT-2A 5-HT2 receptor 5-HT2A receptor 5-HT2A/2C 5-HT2A/2C receptor 5-hydroxytryptamine (serotonin) receptor 2A G protein-coupled 5-hydroxytryptamine 2 receptor 5HT2A Receptor serotonin 5-HT-2A receptor serotonin 5HT-2 receptor serotonin 5HT2 receptor serotonin receptor serotonin receptor 2A SR2A |
| Molecular Weight(MW) |
52kDa(observed:34kDa) |
| Source |
Rabbit |
| Cellular Localization |
Cell membrane;Cell projection, dendrite;Cell projection, axon;Cytoplasmic vesicle;Membrane, caveola;Presynapse |