ICC/IF
Immunofluorescence analysis of Hela cells using WNK4 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-WNK4 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | WNK4 |
|---|---|
| Gene Synonyms | 2010002J11Rik Ac2-059 PHA2B PRKWNK4 |
| Gene Full Name | WNK lysine deficient protein kinase 4 |
| Gene Summary | This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.[provided by RefSeq, Sep 2009] |
| Alternative Names | PRKWNK4 protein kinase protein kinase lysine-deficient 4 protein kinase with no lysine 4 protein kinase lysine deficient 4 RP23-281C18.8 WNK4 Ser/Thr kinase |
| Molecular Weight(MW) | 134kDa(observed：72kDa) |
| Source | Rabbit |
| Cellular Localization | Cell junction, tight junction |
| SwissProt ID | Q96J92 |
|---|
ICC/IF
Immunofluorescence analysis of Hela cells using WNK4 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
