Immunofluorescence analysis of HUVEC cells using MMP9 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
Alternative Names
92 kDa gelatinase 92 kDa type IV collagenase 92kD gelatinase 92kD type IV collagenase CLG4B collagenase type IVB gelatinase B Gelatinase-B GELB macrophage gelatinase matrix metallo protease matrix metallopeptidase 9 (gelatinase B 92kDa gelatinase 92kDa type IV collagenase) matrix metalloproteinase matrix metalloproteinase 9 (gelatinase B 92kDa gelatinase 92kDa type IV collagenase) matrix metalloproteinase 9 (gelatinase B 92kDa matrix metalloproteinase 9 (gelatinase B 92kDa gelatinase 92kDa type IV collagenase) Matrix metalloproteinase9 MMP MMP-9 MMP9 MMPs type V collagenase
Immunofluorescence analysis of HUVEC cells using MMP9 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05% PC300,40% Glycerol.