WB
Western blot analysis using AKR1C1 antibody against C2C12(1),Huvec(2) cell .IHC
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissues using AKR1C1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using AKR1C1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using AKR1C1 antibody with DAB staining.| Product Name | Anti-AKR1C1 antibody-poly-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | poly-HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | AKR1C1 |
|---|---|
| Gene Synonyms | 2-ALPHA-HSD 20-ALPHA-HSD 3alpha-HSD Akr1c1 DD1 DD1/DD2 DDH DDH1 H-37 HAKRC HBAB Hsd17b5 MBAB |
| Gene Full Name | aldo-keto reductase family 1 member C1 |
| Gene Summary | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008] |
| Alternative Names | 17-beta-HSD 5 17HSD type 5 20 alpha-hydroxysteroid dehydrogenase 20alpha-hydroxysteroid dehydrogenase 3beta-hydroxysteroid 3-dehydrogenase aldo-keto reductase C aldo-keto reductase family 1 member C1 (aldehyde reductase) chlordecone reductase homolog chlordecone reductase homolog HAKRC dihydrodiol dehydrogenase 1 dihydrodiol dehydrogenase 1/2 dihydrodiol dehydrogenase 1 20-alpha (3-alpha)-hydroxysteroid dehydrogenase estradiol 17-beta-dehydrogenase (A-specific) hepatic dihydrodiol dehydrogenase high-affinity hepatic bile acid-binding protein hydroxysteroid 17-beta dehydrogenase 5 indanol dehydrogenase oxidoreductase RP11-69D4.1 trans-1 2-dihydrobenzene-1 2-diol dehydrogenase type II 3-alpha-hydroxysteroid dehydrogenase |
| Molecular Weight(MW) | 36kDa |
| Source | Rabbit |
| Cellular Localization | Cytoplasm, cytosol |
| SwissProt ID | Q04828 |
|---|
WB
Western blot analysis using AKR1C1 antibody against C2C12(1),Huvec(2) cell .
IHC
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissues using AKR1C1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using AKR1C1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using AKR1C1 antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
