ICC/IF
Immunofluorescence analysis of Hela cells using GZMH antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-GZMH antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | GZMH |
|---|---|
| Gene Synonyms | C11 CCP-1/C11 CCP-X CCP1 CCPI CGL-1 CGL-2 CGL1 CSP-B CSP-C CSPB Ctla-1 CTLA1 CTSGL1 CTSGL2 GZB HLP RNKP-1 SECT |
| Gene Full Name | granzyme H |
| Gene Summary | This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14. [provided by RefSeq, Nov 2015] |
| Alternative Names | alternatively spliced cathepsin G-like 1 cathepsin G-like 2 protein h-CCPX CGL-2 CGL2 CTLA1 cytotoxic cell protease 1 cytotoxic serine protease B cytotoxic T-lymphocyte proteinase cytotoxic T-lymphocyte proteinase 2 cytotoxic T-lymphocyte-associated serine esterase 1 cytotoxin serine protease-C cytotoxin serine protease-C precursor fragmentin fragmentin 2 fragmentin-2 GLP I GLP III GLP-1 granzyme B (granzyme 2 cytotoxic T-lymphocyte-associated serine esterase 1) granzyme-like protein 1 granzyme-like protein I Gzmb GZMH GZMH/GZMB human lymphocyte protein natural killer cell protease 1 proteolytic serine esterase serine protease serine protease-like protein precursor T-cell serine protease 1-3E T-cell specific protein CCPI precursor |
| Molecular Weight(MW) | 27kDa |
| Source | Rabbit |
| Cellular Localization | Cytolytic granule |
| SwissProt ID | P20718 |
|---|
ICC/IF
Immunofluorescence analysis of Hela cells using GZMH antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
