| Gene Symbol |
CCL17
|
| Gene Synonyms |
A-152E5.3 ABCD-2 SCYA17 Scya17l TARC |
| Gene Full Name |
C-C motif chemokine ligand 17 |
| Gene Summary |
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014] |
| Alternative Names |
activated B and dendritic cell-derived protein C-C motif chemokine CC chemokine TARC chemokine (C-C motif) ligand 17 small inducible cytokine subfamily A (Cys-Cys) member 17 small inducible cytokine subfamily A17 small-inducible cytokine A17 T cell-directed CC chemokine TARC CC chemokine thymus and activation-regulated chemokine |
| Molecular Weight(MW) |
10kDa |
| Source |
Rabbit |
| Cellular Localization |
Secreted |