ICC/IF
Immunofluorescence analysis of Hela cells using LIFR antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-LIFR antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | LIFR |
|---|---|
| Gene Synonyms | A230075M04Rik CD118 LIF LIF-R SJS2 STWS SWS |
| Gene Full Name | LIF receptor subunit alpha |
| Gene Summary | This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2018] |
| Alternative Names | CD118 antigen D-factor/LIF receptor FLJ98106 FLJ99923 higher MW cellular form from non-spliced full CDS leukemia inhibitor factor receptor alpha-chain leukemia inhibitory factor receptor alpha leukemia inhibitory factor receptor alpha chain LIF R beta LIF receptor alpha LIF-R soluble differentiation-stimulating factor receptor Soluble lower MW form from alternatively spliced prematurely terminated CDS |
| Molecular Weight(MW) | 123kDa（observed：220kDa) |
| Source | Rabbit |
| Cellular Localization | Cell membrane;Secreted |
| SwissProt ID | P42702 |
|---|
ICC/IF
Immunofluorescence analysis of Hela cells using LIFR antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
