The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Alternative Names
DKFZp686O0962 G alpha o G protein GNAO 1 Go alpha Go alpha-1a subunit splice variant Go alpha-1b subunit splice variant GO2-q chimeric G-protein GTP-binding protein GTP-binding protein alpha o GTP-binding protein alpha subunit (G0A-alpha) GTP-binding protein alpha subunit (G0B-alpha) GTP-binding protein alpha-o subunit guanine nucleotide binding protein (G protein) alpha activating activity polypeptide O guanine nucleotide binding protein alpha O polypeptide 1 Guanine nucleotide-binding protein alpha subunit guanine nucleotide-binding regulatory protein 2 heterotrimeric guanine nucleotide-binding protein 1G