Immunofluorescence analysis of U251 cells using PPBP antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.
The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014]
Alternative Names
beta-thromboglobulin C-X-C motif chemokine 7 chemokine (C-X-C motif) ligand 7 connective tissue-activating peptide III CXC chemokine ligand 7 leukocyte-derived growth factor low-affinity platelet factor IV macrophage-derived growth factor neutrophil-activating peptide 2 PPBP small inducible cytokine B7 small inducible cytokine subfamily B member 7 thrombocidin 1 thrombocidin 2 thromboglobulin beta-1
Immunofluorescence analysis of U251 cells using PPBP antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05% PC300,40% Glycerol.