| Product Name | Anti-POLR2A antibody-RBITC |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | RBITC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | POLR2A |
|---|---|
| Gene Synonyms | 220kDa DUN2 hRPB220 hsRPB1 NEDHIB POLR2 POLRA RPB1 RPBh1 RpIILS RPO2 Rpo2-1 RPOL2 YNL262W |
| Gene Full Name | RNA polymerase II subunit A |
| Gene Summary | This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008] |
| Alternative Names | 3'-5' exoribonuclease DNA-directed RNA polymerase II largest subunit RNA polymerase II 220 kd subunit DNA-directed RNA polymerase II subunit A DNA-directed RNA polymerase III largest subunit EC 2.7.7.6 MGC75453 Pol II S2p polymerase (RNA) II (DNA directed) polypeptide A 220kDa polymerase (RNA) II subunit A POLYMERASE II RNA RNA POL2 RNA polymerase II RNA polymerase II 1 RNA polymerase II C-terminal domain RNA polymerase II carboxy-terminal domain RNA polymerase II subunit B1 RNA-directed RNA polymerase II subunit RPB1 RP02 RPB220 RPO21 SUA8 |
| Molecular Weight(MW) | 217kDa（observed：65kDa) |
| Source | Rabbit |
| Cellular Localization | Nucleus;Cytoplasm;Chromosome |
| SwissProt ID | P24928 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
