Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Involved in negative regulation of transcription by RNA polymerase II. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Alternative Names
FLAP (FLI LRR associated protein) FLAP-1 FLI-LRR-associated protein 1 GC-binding factor 2 H186 FLAP HUFI1 leucine rich repeat (in FLII) interacting protein 1 LRR FLII-interacting protein 1 NEDD8-conjugating enzyme TAR RNA-interacting protein