| Product Name | Anti-IL5RA antibody-RBITC |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | RBITC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | IL5RA |
|---|---|
| Gene Synonyms | CD125 CDw125 HSIL5R3 IL5R |
| Gene Full Name | interleukin 5 receptor subunit alpha |
| Gene Summary | The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011] |
| Alternative Names | CD125 antigen IL-5 receptor alpha chain IL-5 receptor subunit alpha IL-5R subunit alpha interleukin 5 receptor type 3 interleukin 5 receptor alpha interleukin-5 receptor alpha chain |
| Molecular Weight(MW) | 47kDa |
| Source | Rabbit |
| Cellular Localization | Membrane |
| SwissProt ID | Q01344 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
