| Product Name | Anti-CYP2B6 antibody-RBITC |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | RBITC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CYP2B6 |
|---|---|
| Gene Synonyms | CPB6 CYP2B CYP2B11 Cyp2b6 CYP2B7 CYPIIB11 CYPIIB3 CYPIIB6 EFVM IIB1 P450 |
| Gene Full Name | cytochrome P450 family 2 subfamily B member 6 |
| Gene Summary | This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008] |
| Alternative Names | 1 4-cineole 2-exo-monooxygenase cytochrome P450 2B3-like cytochrome P450 IIB1 cytochrome P450 PBD-2 cytochrome P450 family 2 subfamily B polypeptide 11 cytochrome P450 family 2 subfamily B polypeptide 6 cytochrome P450 subfamily IIB (phenobarbital-inducible) polypeptide 6 cytochrome P450-IIB cytochrome P450IIB3 cytochrome PB24 Cytochrome-P450-2B11 |
| Molecular Weight(MW) | 56kDa |
| Source | Rabbit |
| Cellular Localization | Endoplasmic reticulum membrane;Microsome membrane |
| SwissProt ID | P20813 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
