ICC/IF
Immunofluorescence analysis of SK-N-SH cells using GSTA4 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-GSTA4 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Antigen peptide affinity chromatography |
| Gene Symbol | GSTA4 |
|---|---|
| Gene Synonyms | GST5.7 GSTA4-4 GTA4 mGsta4 |
| Gene Full Name | glutathione S-transferase alpha 4 |
| Gene Summary | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis. [provided by RefSeq, Jul 2008] |
| Alternative Names | glutathione S-alkyltransferase A4 glutathione S-aralkyltransferase A4 glutathione S-aryltransferase A4 glutathione S-transferase glutathione S-transferase 5.7 glutathione S-transferase A4 glutathione S-transferase A4-4 glutathione S-transferase Yk glutathione transferase glutathione transferase A4-4 GST 8-8 GST A4-4 GST class-alpha member 4 GST K GST Yk GSTA4-4 S-(hydroxyalkyl)glutathione lyase A4 |
| Molecular Weight(MW) | 25kDa |
| Source | Rabbit |
| Cellular Localization | Cytoplasm |
| SwissProt ID | O15217 |
|---|
ICC/IF
Immunofluorescence analysis of SK-N-SH cells using GSTA4 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
