| Gene Symbol |
COL8A2
|
| Gene Synonyms |
FECD FECD1 PPCD PPCD2 |
| Gene Full Name |
collagen type VIII alpha 2 chain |
| Gene Summary |
This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
| Alternative Names |
collagen VIII alpha-2 polypeptide collagen type VIII alpha 2 endothelial collagen procollagen type VIII alpha 2 |
| Molecular Weight(MW) |
67kDa(observed:64kDa) |
| Source |
Rabbit |
| Cellular Localization |
Secreted, extracellular space, extracellular matrix, basement membrane |