ICC/IF
Immunofluorescence analysis of A549 cells using CDC6 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-CDC6 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CDC6 |
|---|---|
| Gene Synonyms | CDC18L HsCDC18 HsCDC6 MGORS5 p62(cdc6) |
| Gene Full Name | cell division cycle 6 |
| Gene Summary | The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008] |
| Alternative Names | cdc18-related protein CDC6 cell division cycle 6 homolog CDC6-related protein cell division control protein 6 homolog cell division cycle 6 homolog p62(cdc6) |
| Molecular Weight(MW) | 62kDa（observed：58kDa) |
| Source | Rabbit |
| Cellular Localization | Nucleus;Cytoplasm |
| SwissProt ID | Q99741 |
|---|
ICC/IF
Immunofluorescence analysis of A549 cells using CDC6 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
