ICC/IF
Immunofluorescence analysis of A549 cells using RTN4 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-RTN4 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Antigen peptide affinity chromatography |
| Gene Symbol | RTN4 |
|---|---|
| Gene Synonyms | 1110020G17Rik ASY C130026I10Rik mKIAA0886 mKIAA4153 Nbla00271 Nbla10545 NgA NI-250 NI220/250 NOGO Nogo-A Nogo-B Nogo-C NOGOA NOGOB NSP NSP-CL rat N rat NogoA RTN-X RTN4-A RTN4-B1 RTN4-B2 RTN4-C Vp20 |
| Gene Full Name | reticulon 4 |
| Gene Summary | This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| Alternative Names | ASY foocen glut4 vesicle 20 kDa protein GLUT4 vesicle 20kDa protein Human NogoA My043 protein neurite growth inhibitor 220 neurite outgrowth inhibition RTN4 foocen neurite outgrowth inhibitor neuroendocrine-specific protein C homolog NI-220/250 NOGO-A RTN4-A NOGO-B RTN4-B1 NOGO-C RNT4-C NOGO-C RTN4-C reticulon reticulon 5 RTN4-Aa RTN4-Ab RTN4-B2 RTN4-D RTN4-E RTN4-F RTN4-G RTN4 foocen RTN4a RTN4b RTN4c vp20 |
| Molecular Weight(MW) | 129kDa（observed：40-55kDa) |
| Source | Rabbit |
| Cellular Localization | Endoplasmic reticulum membrane;Cell membrane;Synapse;Cell junction |
| SwissProt ID | Q9NQC3 |
|---|
ICC/IF
Immunofluorescence analysis of A549 cells using RTN4 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
