| Product Name | Anti-SPATA18 antibody-Biotin |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | Biotin |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | SPATA18 |
|---|---|
| Gene Synonyms | 1700067I02Rik Mieap spetex-1 SPETEX1 |
| Gene Full Name | spermatogenesis associated 18 |
| Gene Summary | This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] |
| Alternative Names | spermatid-expressing gene 1 protein spermatid-expressing gene-1 spermatogenesis associated 18 homolog spermatogenesis-associated protein 18 spetex-1 testis tissue sperm-binding protein Li 71n |
| Molecular Weight(MW) | 61kDa（observed：70kDa) |
| Source | Rabbit |
| Cellular Localization | Cytoplasm, cytosol,Mitochondrion outer membrane,Mitochondrion matrix |
| SwissProt ID | Q8TC71 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
