ICC/IF
Immunofluorescence analysis of Hela cells using COL7A1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-COL7A1 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | COL7A1 |
|---|---|
| Gene Synonyms | EBD1 EBDCT EBR1 NDNC8 |
| Gene Full Name | collagen type VII alpha 1 chain |
| Gene Summary | This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008] |
| Alternative Names | collagen vii collagen VII alpha-1 polypeptide collagen type VII alpha 1 HGNC:2214 LC collagen long chain collagen long-chain collagen procollagen type VII alpha 1 |
| Molecular Weight(MW) | 295kDa |
| Source | Rabbit |
| Cellular Localization | Secreted, extracellular space, extracellular matrix, basement membrane |
| SwissProt ID | Q02388 |
|---|
ICC/IF
Immunofluorescence analysis of Hela cells using COL7A1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
