This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011]
Alternative Names
15.2 kDa fatty acid binding protein/FABP/C-FAPB homolog cutaneous fatty acid-binding protein E-FABPPAFABP epidermal-type fatty acid-binding protein epithelial fatty acid-binding protein fatty acid binding protein 5 (psoriasis-associated) fatty acid binding protein 5 epidermal fatty acid-binding protein epidermal keratinocyte lipid-binding protein PA-FABPepidermal psoriasis-associated fatty acid-binding protein homolog