ICC/IF
AF488 staining on IF;Sample: HepG2 cellPrimary Ab: 30µg/ml Mouse Anti-Human F11 AntibodySecond Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody| Product Name | Monoclonal Antibody to Coagulation Factor XI (F11) |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | RPB834Hu01-Recombinant Coagulation Factor XI (F11) |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2aKappa |
| Host Species | Mouse |
| Tested Applications | ICC/IF |
| ICC/IF: 5-30µg/mL |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A/G |
| Gene Symbol | F11 |
|---|---|
| Gene Synonyms | FXI,PTA |
| Gene Full Name | coagulation factor XI |
| Gene Summary | This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008] |
| Alternative Names | FXI PTA Fletcher Factor Prekallikrein Plasma Thromboplastin Antecedent |
ICC/IF
AF488 staining on IF;Sample: HepG2 cellPrimary Ab: 30µg/ml Mouse Anti-Human F11 AntibodySecond Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody| Application Notes | ICC/IF: 5-30µg/mL |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol. |
